ChemicalBook >> CAS DataBase List >>Enalapril
Enalapril
- CAS No.
- 75847-73-3
- Chemical Name:
- Enalapril
- Synonyms
- Vasotec;Renitec;G1ioten;Hipoartd;ENALAPRIL;Enalapril hydrate;Enalapril (MK-421);ELAPRILAT DIHYDRAT;Enalapril USP/EP/BP;Enalapril AldrichCPR
- CBNumber:
- CB1295108
- Molecular Formula:
- C20H28N2O5
- Molecular Weight:
- 376.45
- MDL Number:
- MFCD00865774
- MOL File:
- 75847-73-3.mol
- MSDS File:
- SDS
Last updated:2024-05-18 11:31:11
Melting point | 142-147℃ |
---|---|
Boiling point | 582.4±50.0 °C(Predicted) |
Density | 1.204±0.06 g/cm3(Predicted) |
RTECS | TW3665500 |
storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
solubility | Soluble in DMSO |
form | Powder |
pka | pKa 2.97 (H2O t=25.0)(Approximate);5.35(H2O t=25.0)(Approximate) |
Water Solubility | Soluble in water at 25mg/ml |
BCS Class | 3 |
CAS DataBase Reference | 75847-73-3(CAS DataBase Reference) |
NCI Dictionary of Cancer Terms | |
FDA UNII | |
NCI Drug Dictionary | |
ATC code | |
EPA Substance Registry System |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07,GHS08 |
---|---|
Signal word | Warning |
Hazard statements | H317-H361 |
Precautionary statements | P280 |
Safety Statements | 22-24/25 |
WGK Germany | 3 |
Enalapril price More Price(20)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Alfa Aesar | J60750 | Enalapril | 75847-73-3 | 1g | $93.65 | 2025-03-01 | Buy |
Alfa Aesar | J60750 | Enalapril | 75847-73-3 | 5g | $369.65 | 2025-03-01 | Buy |
Cayman Chemical | 16041 | Enalapril ≥98% | 75847-73-3 | 5g | $165 | 2022-12-16 | Buy |
Cayman Chemical | 16041 | Enalapril ≥98% | 75847-73-3 | 1g | $48 | 2022-12-16 | Buy |
Cayman Chemical | 16041 | Enalapril ≥98% | 75847-73-3 | 10g | $270 | 2022-12-16 | Buy |
Enalapril Chemical Properties,Uses,Production
Uses
It is used for hypertension and chronic cardiac insufficiency.Uses
angiotensin converting enzyme inhibitorUses
Enalapril is used in the treatment of hypertension, diabetic nephropathy, and some types of chronic heart failure. It has been proven to protect the function of the kidneys in hypertension, heart failure, and diabetes, and may be used in the absence of hypertension for its kidney protective effects. It is widely used in chronic kidney failure.Definition
ChEBI: A dicarboxylic acid monoester that is ethyl 4-phenylbutanoate in which a hydrogen alpha to the carboxy group is substituted by the amino group of L-alanyl-L-proline (S-configuration).Mechanism of action
Like captopril, enalapril selectively suppresses the rennin–angiotensin–aldosterone system, inhibits angiotensin-converting enzyme, and prevents conversion of angiotensin I into angiotensin II.Synthesis
Enalapril, (S)-1-[N-[1-(ethoxycarbonyl)-3-phenylpropyl]-L-alanyl]-L-proline (22.7.12), is synthesized by reacting the benzyl ester of L-alanyl-L-proline with the ethyl ester of 3-benzoylacrylic acid, which forms the product 22.7.11, the reduction of which with hydrogen using a Raney nickel catalyst removes the protective benzyl group, giving the desired enalapril (22.7.12) [24]. Alternative methods of syntheses have also been proposed.
Enalapril Preparation Products And Raw materials
Raw materials
1of5
Preparation Products
Global( 184)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Jiangxi Huihe Chemical Co., Ltd. | +86-19189228086 +8618858568638 | wuzhouding@huihecrop.com | China | 886 | 58 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21695 | 55 |
career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
Xi'an MC Biotech, Co., Ltd. | 029-89275612 +8618991951683 | mcbio_sales@163.com | China | 2255 | 58 |
Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 | 1026@dideu.com | China | 9705 | 58 |
Hebei Lingding Biotechnology Co., Ltd. | +86-18031140164 +86-19933155420 | erin@hbldbiotech.com | China | 879 | 58 |
Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 29627 | 58 |
View Lastest Price from Enalapril manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2022-10-20 | Enalapril
75847-73-3
|
US $200.00 / KG | 1KG | 99% | 9000kg/per week | Hebei Lingding Biotechnology Co., Ltd. | ||
2022-08-12 | Enalapril
75847-73-3
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd | ||
2022-08-11 | Enalapril USP/EP/BP
75847-73-3
|
US $1.10 / g | 1g | 99.9% | 100 Tons min | Dideu Industries Group Limited |
- Enalapril
75847-73-3
- US $200.00 / KG
- 99%
- Hebei Lingding Biotechnology Co., Ltd.
- Enalapril
75847-73-3
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
- Enalapril USP/EP/BP
75847-73-3
- US $1.10 / g
- 99.9%
- Dideu Industries Group Limited
75847-73-3(Enalapril)Related Search:
ENALAPRIL
(s)-1-(n-(1-(ethoxycarbonyl)-3-phenylpropyl)-l-alanyl)-l-proline
1-(n-((s)-1-carboxy-3-phenylpropyl)-l-alanyl)-l-proline 1'-ethyl ester
1-[2-(1-ETHOXYCARBONYL-3-PHENYL-PROPYL)AMINOPROPANOYL]PYRROLIDINE-2-CARBOXYLIC ACID
Renitec
Enalapril Maleate USP24
L-Proline, 1-[N-[1-(ethoxycarbonyl)-3-phenylpropyl]-L-alanyl]-, (S)-
L-Proline, N-[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]-L-alanyl-
(-)-1-[N-[(S)-1-(Ethoxycarbonyl)-3-phenylpropyl]-L-alanyl]-L-proline
1-[N-[(S)-1-(Ethoxycarbonyl)-3-phenylpropyl]-L-alanyl]-L-proline
N-[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]-L-Ala-L-Pro-OH
N-[(S)-1-(Ethoxycarbonyl)-3-phenylpropyl]-L-Ala-L-Pro-OH
(S)-1-((S)-2-(((S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl)aMino)propanoyl)pyrrolidine-2-carboxylic acid
Enalapril AldrichCPR
(S)-1-[N-[1-(Ethoxyearbonyl)-3-phenylpropyl]-L-alanyl]-L-proline
G1ioten
Hipoartd
(2S)-1-[(2S)-2-[[(2S)-1-Ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]pyrrolidine-2-carboxylic acid
(S)-N-[1-Ethoxycarbonyl)-3-phenylpropyl]-Ala-Pro
N-[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]-L-alanyl-L-proline
Enalapril hydrate
Enalapril USP/EP/BP
Enalaprilat dihydrat
EnalaprilQ: What is
Enalapril Q: What is the CAS Number of
Enalapril Q: What is the storage condition of
Enalapril Q: What are the applications of
Enalapril
Vasotec
Enalapril (MK-421)
ELAPRILAT DIHYDRAT
75847-73-3
C20H28N2O5
Angiotensin