ChemicalBook >> CAS DataBase List >>Faropenem sodium hemipentahydrate
Faropenem sodium hemipentahydrate
- CAS No.
- 106560-14-9
- Chemical Name:
- Faropenem sodium hemipentahydrate
- Synonyms
- FROPENEM;FAROPENEM;Faropenem sodium hemi 5-hydrate;Faropenem sodium hemipentahydrate;Faropenem sodium hemipentahydrate USP/EP/BP;6α-[(R)-1-hydroxyethyl]-2-[(R)-tetrahydrofuran-2-yl]pen-2-em-3-carboxylic acid;(5R,6S,8R,2'R)-2-(2'-tetrahydrofuryl)-6-(1-hydroxyethyl)-2-penem-3-carboxylic acid;6alpha-[(R)-1-hydroxyethyl]-2-[(R)-tetrahydrofuran-2-yl]pen-2-em-3-carboxylic acid;(5R,6S)-6-[(1R)-1-hydroxyethyl]-7-oxo-3-[(2R)-2-oxolanyl]-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid;(5R,6S)-6-[(1R)-1-hydroxyethyl]-7-oxo-3-[(2R)-oxolan-2-yl]-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
- CBNumber:
- CB1300660
- Molecular Formula:
- C12H15NO5S
- Molecular Weight:
- 285.32
- MDL Number:
- MFCD00868867
- MOL File:
- 106560-14-9.mol
Last updated:2024-05-04 17:34:31
Boiling point | 570.2±50.0 °C(Predicted) |
---|---|
Density | 1.56±0.1 g/cm3(Predicted) |
pka | 4.00±0.40(Predicted) |
CAS DataBase Reference | 106560-14-9 |
FDA UNII | |
ATC code |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H302-H315-H319-H335 |
Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 |
Faropenem sodium hemipentahydrate price More Price(6)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
TRC | F103303 | Faropenem | 106560-14-9 | 100mg | $580 | 2022-12-16 | Buy |
American Custom Chemicals Corporation | API0002771 | FROPENEM 95.00% | 106560-14-9 | 5G | $927.76 | 2022-12-16 | Buy |
AHH | API-1035 | Fropenem 98% | 106560-14-9 | 100mg | $600 | 2022-12-16 | Buy |
AvaChem | 1723A | Faropenem | 106560-14-9 | 10mg | $39 | 2022-12-16 | Buy |
AvaChem | 1723A | Faropenem | 106560-14-9 | 100mg | $89 | 2022-12-16 | Buy |
Faropenem sodium hemipentahydrate Chemical Properties,Uses,Production
Description
Farom was launched in Japan for use as an antibiotic against common respiratory tract pathogens. It can be prepared by several related routes of about seven steps starting with tetrahydrofuran-2-thiocarboxylic acid and a silylated azetidinone. It is a broad spectrum oral penem antibiotic that is β-lactamase stable. Farom is the most active β-lactam against anaerobes (more than cefaclor, cefixime and amoxicillin) but also has activity against Gram-positive, Gram-negative and enterobacteriaceae. It is equally active against strains carrying plasmid and chromosome mediated β-lactamases. The short plasma elimination half-life is the result of hydrolysis by renal dehydropeptidase. It is more stable to hydrolysis by extended spectrum β-lactamases than some second and third generation cephalosporins.Originator
Suntory (Japan)Uses
Treatmentof bacterial infections.Uses
Faropenem (cas# 106560-14-9) is a compound useful in organic synthesis.Definition
ChEBI: 6alpha-[(R)-1-hydroxyethyl]-2-[(R)-tetrahydrofuran-2-yl]pen-2-em-3-carboxylic acid is a faropenem. It is a conjugate acid of a 6alpha-[(R)-1-hydroxyethyl]-2-[(R)-tetrahydrofuran-2-yl]pen-2-em-3-carboxylate.brand name
FaromAntimicrobial activity
An orally active penem with a broad spectrum of antibacterial activity, including activity against selected anaerobic pathogens. Although it is active against most enterobacteria, it has reduced activity against Ser. marcescens, Enterobacter spp. and some Providencia spp. It generally retains activity against many Gram-positive organisms, but has no useful activity against Ps. aeruginosa. It has reduced activity against E. faecium, methicillin-resistant Staph. aureus (MRSA) and some strains of coagulase-negative staphylococci. It is stable to hydrolysis by extended spectrum β-lactamases, but is hydrolyzed by carbapenemases. Esterified prodrugs with increased bioavailability have been studied in clinical trials but have not received regulatory approval.Faropenem sodium hemipentahydrate Preparation Products And Raw materials
Raw materials
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Preparation Products
Global( 135)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21697 | 55 |
career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
Xiamen AmoyChem Co., Ltd | +86-592-6051114 +8618959220845 | sales@amoychem.com | China | 6387 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 47465 | 58 |
Shaanxi Dideu Medichem Co. Ltd | +86-29-87569265 +86-18612256290 | 1056@dideu.com | China | 3959 | 58 |
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21149 | 58 |
SIMAGCHEM CORP | +86-13806087780 | sale@simagchem.com | China | 17367 | 58 |
HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6313 | 58 |
Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 | 1026@dideu.com | China | 9802 | 58 |
Related articles
- Faropenem: Antimicrobial Activity, Susceptibility, Toxicity and Clinical Uses
- Faropenem is a penem-class oral b-lactam antimicrobial agent. Although faropenem is structurally similar to the carbapenems, i....
- Apr 13,2022
- Pharmacokinetics of Faropenem
- Faropenem is effective against common community-acquired pathogens, such as Streptococcus pneumoniae, Haemophilus influenzae, ....
- Mar 9,2022
View Lastest Price from Faropenem sodium hemipentahydrate manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2023-04-18 | Faropenem Sodium Hydrate
106560-14-9
|
US $0.00-0.00 / mg | 10mg | 90%+ | 10g | Guangzhou PI PI BIOTECH INC | ||
2022-07-20 | Faropenem sodium hemipentahydrate
106560-14-9
|
US $1.00-1.00 / KG | 1g | 99% | 50tons | Shaanxi Dideu Medichem Co. Ltd | ||
2022-06-22 | Faropenem sodium hemipentahydrate USP/EP/BP
106560-14-9
|
US $1.10 / g | 1g | 99.9% | 100 Tons Min | Dideu Industries Group Limited |
- Faropenem Sodium Hydrate
106560-14-9
- US $0.00-0.00 / mg
- 90%+
- Guangzhou PI PI BIOTECH INC
- Faropenem sodium hemipentahydrate
106560-14-9
- US $1.00-1.00 / KG
- 99%
- Shaanxi Dideu Medichem Co. Ltd
- Faropenem sodium hemipentahydrate USP/EP/BP
106560-14-9
- US $1.10 / g
- 99.9%
- Dideu Industries Group Limited
106560-14-9(Faropenem sodium hemipentahydrate)Related Search:
1of4
[5R-[3(R^<*>^),5α,6α(R^<*>^)]]-6-(1-hydroxyethyl)-7-oxo-3-(tetrahydro-2-furanyl)-4-thia-1-azobicyclo[3.2.0]leapt-2- ene-2-carboxylicacid
(5R,6S)-6-[(1R)-1-hydroxyethyl]-7-keto-3-[(2R)-tetrahydrofuran-2-yl]-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
(5R,6S)-6-[(1R)-1-hydroxyethyl]-7-oxo-3-[(2R)-oxolan-2-yl]-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
6alpha-[(R)-1-hydroxyethyl]-2-[(R)-tetrahydrofuran-2-yl]pen-2-em-3-carboxylic acid
(+)-(5R,6S)-6-[(1R)-1-Hydroxyethyl]-7-oxo-3-[(2R)-tetrahydro-2-furyl]-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
(5R,6S,8R,2'R)-2-(2'-tetrahydrofuryl)-6-(1-hydroxyethyl)-2-penem-3-carboxylic acid
4-Thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 6-(1-hydroxyethyl)-7-oxo-3-(tetrahydro-2-furanyl)-, [5R-[3(R*),5α,6α(R*)]]-
4-Thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 6-[(1R)-1-hydroxyethyl]-7-oxo-3-[(2R)-tetrahydro-2-furanyl]-, (5R,6S)-
6-[(1R)-1-Hydroxyethyl]-7-oxo-3-[(2R)-tetrahydro-2-furanyl]-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid monosodium salt hemipentahydrate
Faropenem sodium hemipentahydrate
FAROPENEM
FROPENEM
(5R,6R)-6-[(1R)-1-hydroxyethyl]-7-oxo-3-[(2R)-tetrahydrofuran-2-yl]-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
(5R,6S)-6-[(1R)-1-hydroxyethyl]-7-oxo-3-[(2R)-2-oxolanyl]-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
6α-[(R)-1-hydroxyethyl]-2-[(R)-tetrahydrofuran-2-yl]pen-2-em-3-carboxylic acid
Faropenem sodium hemipentahydrate USP/EP/BP
(5R,6S)-6-((R)-1-Hydroxyethyl)-7-oxo-3-((R)-tetrahydrofuran-2-yl)-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
Faropenem-d5Q: What is
Faropenem-d5 Q: What is the CAS Number of
Faropenem-d5 Q: What are the applications of
Faropenem-d5
Faropenem sodium hemi 5-hydrate
106560-14-9
22547-49-3
2C12H14NNaO5S5H20
2C12H14NO5S2Na5H2O
API