ChemicalBook >> CAS DataBase List >>2-Chloro-5-fluoropyrimidine
2-Chloro-5-fluoropyrimidine
- CAS No.
- 62802-42-0
- Chemical Name:
- 2-Chloro-5-fluoropyrimidine
- Synonyms
- 2-Chloro-5-fluoropyr;Fampridine Impurity 213;2-CHLORO-5-FLUOROPYRIMIDINE;2-Chloro-5-fluoropyriMidi...;Pyrimidine,2-chloro-5-fluoro-;2-Chloro-5-fluoro-1,3-diazine;2-Chloro-5-fluoropyrimidine >2-Chloro-5-fluoropyrimidine ,98%;Pyrimidine, 2-chloro-5-fluoro- (9CI);2-Chloro-5-fluoropyrimidine ISO 9001:2015 REACH
- CBNumber:
- CB5343151
- Molecular Formula:
- C4H2ClFN2
- Molecular Weight:
- 132.52
- MDL Number:
- MFCD03788197
- MOL File:
- 62802-42-0.mol
- MSDS File:
- SDS
Last updated:2024-04-23 13:52:06
Boiling point | 149.0-162.0°C |
---|---|
Density | 1.439 g/mL at 20 °C (lit.) |
refractive index |
n |
Flash point | 150 °F |
storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
pka | -2.54±0.22(Predicted) |
form | Liquid |
color | Clear colorless to yellow |
InChI | InChI=1S/C4H2ClFN2/c5-4-7-1-3(6)2-8-4/h1-2H |
InChIKey | AGYUQBNABXVWMS-UHFFFAOYSA-N |
SMILES | C1(Cl)=NC=C(F)C=N1 |
CAS DataBase Reference | 62802-42-0(CAS DataBase Reference) |
FDA UNII |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS05,GHS07 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Signal word | Danger | |||||||||
Hazard statements | H302-H314 | |||||||||
Precautionary statements | P270-P280-P301+P312-P303+P361+P353-P304+P340+P310-P305+P351+P338 | |||||||||
Hazard Codes | Xn,Xi | |||||||||
Risk Statements | 22-34-41-37/38 | |||||||||
Safety Statements | 26-36/37/39-45 | |||||||||
RIDADR | UN 2735 8/PG 2 | |||||||||
WGK Germany | 3 | |||||||||
Hazard Note | Harmful | |||||||||
HazardClass | IRRITANT | |||||||||
HazardClass | 8 | |||||||||
PackingGroup | Ⅲ | |||||||||
HS Code | 29335990 | |||||||||
NFPA 704 |
|
2-Chloro-5-fluoropyrimidine price More Price(37)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 651753 | 2-Chloro-5-fluoropyrimidine 97% | 62802-42-0 | 1g | $183 | 2024-06-20 | Buy |
Sigma-Aldrich | 651753 | 2-Chloro-5-fluoropyrimidine 97% | 62802-42-0 | 250mg | $86.8 | 2024-01-07 | Buy |
TCI Chemical | C2546 | 2-Chloro-5-fluoropyrimidine >98.0%(GC) | 62802-42-0 | 1g | $50 | 2025-03-01 | Buy |
TCI Chemical | C2546 | 2-Chloro-5-fluoropyrimidine >98.0%(GC) | 62802-42-0 | 5g | $149 | 2025-03-01 | Buy |
Alfa Aesar | H55055 | 2-Chloro-5-fluoropyrimidine, 97% | 62802-42-0 | 1g | $144.65 | 2025-03-01 | Buy |
2-Chloro-5-fluoropyrimidine Chemical Properties,Uses,Production
Chemical Properties
Colorless to light yellow liquidUses
2-Chloro-5-fluoropyrimidine is used to prepare 2,4-disubstituted-5-fluoropyrimidine , which is a biologically active molecule seen in anticancer agents like 5-fluorouracil.Uses
2-Chloro-5-fluoropyrimidine can be used as a starting material for the preparation of:
5-fluoro-2-amino pyrimidines by reacting with various amines in the presence of K2CO3, via C-N bond forming reaction.
2-chloro-5-(5-fluoropyrimidin-2-yl)benzoic acid, an intermediate, which is used in the synthesis of benzamide scaffolds as potent antagonists against P2X7 receptors.
5-fluoro-2-cyano pyrimidine, a key intermediate used for the synthesis of 5-chloro-N-[(1S)-1-(5-fluoropyrimidin-2-yl)ethyl]-N-(5-methyl-1H-pyrazol-3-yl)pyrimidine-2,4-diamine, as a potent inhibitor of the JAK2 kinase.
Preparation
Synthesis of 2-chloro-5-fluoropyrimidine: add 2,4-Dichloro-5-fluoropyrimidine and reducing metal powder to the solvent, stir to raise the temperature to the reaction temperature, slowly add acid dropwise, and keep the temperature until the reaction is completed Finish. Filtration, phase separation or direct evaporation of the solvent, and distillation under reduced pressure to remove the solvent to obtain 2-chloro-5-fluoropyrimidine.2-Chloro-5-fluoropyrimidine Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 366)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
WinWin Chemical CO., Limited | +86-0086-577-64498589 +86-15355981851 | sales@win-winchemical.com | China | 13849 | 58 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21699 | 55 |
Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | fandachem@gmail.com | China | 9353 | 55 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
Zhejiang ZETian Fine Chemicals Co. LTD | 18957127338 | stella@zetchem.com | China | 2141 | 58 |
Shanghai Arbor Chemical Co., Ltd. | 021-60451682 | act@arborchemical.com | CHINA | 906 | 58 |
Win-Win Chemical CO., Limited | 0086-577-64498589 | sales@win-winchemical.com | CHINA | 998 | 58 |
Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 7836 | 58 |
View Lastest Price from 2-Chloro-5-fluoropyrimidine manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-02-23 | 2-Chloro-5-fluoropyrimidine
62802-42-0
|
US $0.00 / KG | 1KG | 98%min | 30tons/month | WUHAN FORTUNA CHEMICAL CO., LTD | ||
2023-09-29 | 2-Chloro-5-fluoropyrimidine
62802-42-0
|
US $0.00-0.00 / kg | 1kg | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. | ||
2022-12-04 | 2-Chloro-5-fluoropyrimidine
62802-42-0
|
US $1.10 / g | 1g | 99.00% | 100 Tons Min | Dideu Industries Group Limited |
- 2-Chloro-5-fluoropyrimidine
62802-42-0
- US $0.00 / KG
- 98%min
- WUHAN FORTUNA CHEMICAL CO., LTD
- 2-Chloro-5-fluoropyrimidine
62802-42-0
- US $0.00-0.00 / kg
- 98%
- Henan Aochuang Chemical Co.,Ltd.
- 2-Chloro-5-fluoropyrimidine
62802-42-0
- US $1.10 / g
- 99.00%
- Dideu Industries Group Limited
62802-42-0(2-Chloro-5-fluoropyrimidine)Related Search:
2,4-DICHLORO-6-ETHYL-5-FLUOROPYRIMIDINE
4-AMINO-2-CHLORO-5-FLUOROPYRIMIDINE,4-AMINO-2-CHLORO-5-FLUOROPYRIMIDINE GC 95.0%,2-Chloro-5-fluoropyrimidine-4-amine
2,4-Dichloro-5-fluoropyrimidine
Difluorochloromethane
3-(6-chloro-5-fluoropyrimidin-4-yl)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol
1of4
Pyrimidine, 2-chloro-5-fluoro- (9CI)
2-CHLORO-5-FLUOROPYRIMIDINE
Pyrimidine,2-chloro-5-fluoro-
2-Chloro-5-fluoropyr
2-Chloro-5-fluoropyriMidi...
2-Chloro-5-fluoropyrimidine ,98%
2-Chloro-5-fluoro-1,3-diazine
2-Chloro-5-fluoropyrimidine >
2-Chloro-5-fluoropyrimidine ISO 9001:2015 REACH
Fampridine Impurity 213
62802-42-0
63802-42-0
C4H2ClFN2
Building Blocks
Heterocyclic Building Blocks
Halogenated Heterocycles
Pyrimidines
Halogenated Heterocycles
Heterocyclic Building Blocks
PyrimidinesHeterocyclic Building Blocks
Variety of halogenated heterocyclic series
PYRIMIDINE
Pyrimidine series
pharmacetical
Pyrimidines
Fluorine series
Bases & Related Reagents
Nucleotides
Building Blocks
62802-42-0