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ChemicalBook >> CAS DataBase List >>4-Cyanophenol

4-Cyanophenol

CAS No.
767-00-0
Chemical Name:
4-Cyanophenol
Synonyms
4-HYDROXYBENZONITRILE;4-HYDROXYBENZOHYDRAZIDE;P-CYANOPHENOL;PARA-CYANOPHENOL;Hydroxybenzonitrile;Benzonitrile, 4-hydroxy-;P-nitrile;AKOS 217-25;AKOS B004225;4-CYANOPHENOL
CBNumber:
CB6681698
Molecular Formula:
C7H5NO
Molecular Weight:
119.12
MDL Number:
MFCD00002312
MOL File:
767-00-0.mol
MSDS File:
SDS
Last updated:2024-11-08 15:05:22

4-Cyanophenol Properties

Melting point 110-113 °C(lit.)
Boiling point 146 °C / 2mmHg
Density 1.1871 (rough estimate)
refractive index 1.5800 (estimate)
storage temp. Inert atmosphere,Room Temperature
solubility methanol: 0.1 g/mL, clear
form Crystalline Powder
pka 7.97(at 25℃)
color Off-white to beige-gray
Water Solubility slightly soluble
BRN 386130
Stability Stable. Incompatible with strong oxidizing agents.
CAS DataBase Reference 767-00-0(CAS DataBase Reference)
EWG's Food Scores
FDA UNII
NIST Chemistry Reference
EPA Substance Registry System

SAFETY

Risk and Safety Statements

Symbol(GHS)  sòng bạc tiền thậtLiên kết đăng nhập
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xn,Xi
Risk Statements  22-36/37/38
Safety Statements  26-36-45-24/25
WGK Germany  3
RTECS  DI4375000
Hazard Note  Irritant
TSCA  Yes
HS Code  29269095
NFPA 704
1
2 0

4-Cyanophenol price More Price(42)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich C94009 4-Cyanophenol 95% 767-00-0 5g $36.4 2025-03-01 Buy
TCI Chemical C0842 4-Hydroxybenzonitrile >98.0%(GC)(T) 767-00-0 25g $23 2025-03-01 Buy
TCI Chemical C0842 4-Hydroxybenzonitrile >98.0%(GC)(T) 767-00-0 500g $220 2025-03-01 Buy
Alfa Aesar A15803 4-Hydroxybenzonitrile, 98+% 767-00-0 50g $63.65 2025-03-01 Buy
Alfa Aesar A15803 4-Hydroxybenzonitrile, 98+% 767-00-0 100g $105.65 2025-03-01 Buy
Product number Packaging Price Buy
C94009 5g $36.4 Buy
C0842 25g $23 Buy
C0842 500g $220 Buy
A15803 50g $63.65 Buy
A15803 100g $105.65 Buy

4-Cyanophenol Chemical Properties,Uses,Production

Chemical Properties

white crystalline powder or chips. 4-Hydroxybenzonitrile [767-00-0], 4-cyanophenol, 1-cyano-4-hydroxybenzene, Mr 119.2, forms colorless crystals of mp 113℃. 4-Hydroxybenzonitrile is produced by reaction of 4-bromophenol with copper (I) cyanide, by ammoxidation of p-cresol, by reaction of 4-chlorobenzonitrile with sodium methoxide, or by the catalyzed gas phase reaction of ethyl 4-hydroxybenzoate with ammonia. The nitrile is used for the production of the herbicides 3,5-dibromo- and 3,5-diiodo-4- hydroxybenzonitrile (Bromoxynil, Ioxynil, May & Baker).

Uses

Intermediates of Liquid Crystals

Uses

4-Cyanophenol is a precursor for the synthesis of a vasodilator, Levcromakalim. Bromination of 4-cyanophenol results in bromoxynil, a commercial herbicide. It can also be used as a component of deep eutectic solvent (DES) mixture.

Preparation

4-Cyanophenol is produced by reaction of 4-bromophenol with copper (I) cyanide, by ammoxidation of p-cresol, by reaction of 4-chlorobenzonitrile with sodium methoxide, or by the catalyzed gas phase reaction of ethyl 4-hydroxybenzoate with ammonia.

Definition

ChEBI: 4-cyanophenol is a member of phenols. It has a role as an EC 1.4.3.4 (monoamine oxidase) inhibitor. It is functionally related to a benzonitrile.

Synthesis Reference(s)

The Journal of Organic Chemistry, 39, p. 3343, 1974 DOI:

Purification Methods

Crystallise the phenol from pet ether, *benzene or water and keep it under vacuum over P2O5. [Bernasconi & Paschelis J Am Chem Soc 108 2969 1986.] [Beilstein 10 H 167, 10 IV 441.]
1194-02-1
767-00-0
Synthesis of 4-Cyanophenol from 4-Fluorobenzonitrile
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View Lastest Price from 4-Cyanophenol manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
sòng bạc tiền thậtLiên kết đăng nhập 2024-09-08 4-Cyanophenol
767-00-0
US $50.00 / kg 1kg 99% 10000tons Anhui Ruihan Technology Co., Ltd
sòng bạc tiền thậtLiên kết đăng nhập 2024-03-06 4-Cyanophenol P-Cyanophenol
767-00-0
US $19.00 / KG 1KG 99.% 50 ton Hebei Guanlang Biotechnology Co,.LTD
sòng bạc tiền thậtLiên kết đăng nhập 2024-01-31 4-Cyanophenol
767-00-0
US $0.00 / Kg/Bag 1Kg/Bag 99% 5000kg/month Hebei Mojin Biotechnology Co., Ltd
  • sòng bạc tiền thậtLiên kết đăng nhập
  • 4-Cyanophenol
    767-00-0
  • US $50.00 / kg
  • 99%
  • Anhui Ruihan Technology Co., Ltd
  • sòng bạc tiền thậtLiên kết đăng nhập
  • 4-Cyanophenol
    767-00-0
  • US $0.00 / Kg/Bag
  • 99%
  • Hebei Mojin Biotechnology Co., Ltd
p-hydroxy benzonitrile,p-cyano phenol 4-HYDROXYBENZONITRILE FOR SYNTHESIS AKOS B004225 AKOS 217-25 4-CYANOPHENOL CYANOPHENOL(4-) P-HYDROXYBENZONITRILE p-Cyanolphenol p-hydroxy-benzonitril 4-Hydroxybenzenecarbonitrile P-nitrile Right hydroxybenzonitrile 4-Cyanophenol, 99% 100GR 4-Cyanophenol, 99% 25GR p-Hydroxybenzonitrile 4-Cyanophenol TIMTEC-BB SBB008054 P-Cyanophenol(4-HydroxyBenzonitrile) 4-Cyanophenol99% 4-Hydroxybenzonitrile, 98+% 4-Cyanophenol,98+% 4-HYDROXYBENZONITRILE (P-HYDROXYBENZONITRILE) 4-CYANOPHENOL(4-HYDROXYBENZONITRILE) p-Hydroxybenzonitrile, 4-Hydroxybenzonitrile 4-HYDROXYBENZONITRILE PESTANAL, 250 MG The cyano phenol 4-Hydroxybenzo 4-Cyanolphenol 4-hydroxy-benzonitril 4-Cyanophenol, 97+% Benzonitrile, p-hydroxy- Benzonitrile,4-hydroxy- Febuxostat-21 4-Hydroxybenzonitrile > Hydroxyphenonitrile P-Hydroxybenzonitrite 4-Cyanophenol ISO 9001:2015 REACH 4-Cyanophenol (Febuxostat Impurity) 4-Cyanophenol P-Cyanophenol 4-HYDROXYBENZONITRILE P-CYANOPHENOL Hydroxybenzonitrile 4-HYDROXYBENZOHYDRAZIDE Benzonitrile, 4-hydroxy- PARA-CYANOPHENOL 4-Cyanophenol?New 767-00-0 676-00-0 767-00-1 CNC6H4OH Nitrogen Compounds Organic Building Blocks Cyanides/Nitriles Benzonitriles (Building Blocks for Liquid Crystals) Building Blocks for Liquid Crystals Building Blocks C6 to C7 Aromatic Nitriles Phenoles and thiophenoles
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