ChemicalBook >> CAS DataBase List >>6-Nitroindazole
6-Nitroindazole
- CAS No.
- 7597-18-4
- Chemical Name:
- 6-Nitroindazole
- Synonyms
- 6-NITRO-1H-INDAZOLE;6-Nitrobrazol;6-NITROINDAZOLE;6-Nitroindazoles;6-Nitroisoindazole;6-nitro-1h-indazol;6-Nitroindazole>6-Nitroindazole 97%;6-Nitroindazole,98%;6-Nitroindazole ,97%
- CBNumber:
- CB8358413
- Molecular Formula:
- C7H5N3O2
- Molecular Weight:
- 163.13
- MDL Number:
- MFCD00005695
- MOL File:
- 7597-18-4.mol
- MSDS File:
- SDS
Last updated:2024-12-27 16:49:21
Melting point | 180-182 °C (lit.) |
---|---|
Boiling point | 290.19°C (rough estimate) |
Density | 1.4141 (rough estimate) |
refractive index | 1.5500 (estimate) |
storage temp. | Sealed in dry,Room Temperature |
solubility | very faint turbidity in hot Methanol |
form | Powder |
pka | 11.08±0.40(Predicted) |
color | Light Yellow |
BRN | 7812 |
CAS DataBase Reference | 7597-18-4(CAS DataBase Reference) |
EWG's Food Scores | |
NIST Chemistry Reference | |
EPA Substance Registry System |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07,GHS08 |
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Signal word | Warning | |||||||||
Hazard statements | H302+H312+H332-H315-H319-H335-H351 | |||||||||
Precautionary statements | P280-P301+P312-P302+P352+P312-P304+P340+P312-P305+P351+P338-P308+P313 | |||||||||
Hazard Codes | Xn,Xi | |||||||||
Risk Statements | 20/21/22-36/37/38-40-68-36 | |||||||||
Safety Statements | 26-27-36/37/39 | |||||||||
WGK Germany | 3 | |||||||||
RTECS | NK7962100 | |||||||||
TSCA | Yes | |||||||||
HS Code | 29339900 | |||||||||
NFPA 704 |
|
6-Nitroindazole price More Price(29)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | N17513 | 6-Nitroindazole 97% | 7597-18-4 | 100g | $254 | 2024-06-20 | Buy |
TCI Chemical | N0399 | 6-Nitroindazole >98.0%(GC) | 7597-18-4 | 25g | $34 | 2025-03-01 | Buy |
TCI Chemical | N0399 | 6-Nitroindazole >98.0%(GC) | 7597-18-4 | 250g | $167 | 2025-03-01 | Buy |
Alfa Aesar | A16213 | 6-Nitro-1H-indazole, 97% | 7597-18-4 | 100g | $88 | 2022-12-16 | Buy |
Alfa Aesar | A16213 | 6-Nitro-1H-indazole, 97% | 7597-18-4 | 25g | $35.8 | 2022-12-16 | Buy |
6-Nitroindazole Chemical Properties,Uses,Production
Description
6-Nitroindazole is a competitive and reversible Monoamine oxidase(MAO)inhibitor. It can inhibit MAO-A and MAO-B (IC50= 2.5 μM). Monoamine oxidase (MAO) B is a mitochondrial enzyme selectively involved in the oxidative activation of 1-methyl-4- phenyl-1,2,3,6-tetrahydropyridine (MPTP) neurotoxin to toxic pyridinium cations producing Parkinsonism in animal models. In addition, it is an nNOS inhibitor, which has neuroprotective effects[1].
Chemical Properties
yellow powderUses
Anticonvulsant.Synthesis
6-Nitroindazole is prepared by (2-methyl-5-nitrophenyl)azo phenyl sulfide and 1,8-diazabicyclo[5.4.0]undec-7-ene in the presence of concentrated acetonitrile.
References
[1] HERRAIZTOMAS GuillénHugo AránVicente J. Nitroindazole compounds inhibit the oxidative activation of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) neurotoxin to neurotoxic pyridinium cations by human monoamine oxidase (MAO).[J]. Free Radical Research, 2009: 975-984. DOI:10.1080/10715760903159170.6-Nitroindazole Preparation Products And Raw materials
Raw materials
Preparation Products
6-Iodo-1H-indazole
6-AMINO-2-METHYL-2H-INDAZOLE
(E)-6-Nitro-3-[2-(pyridin-2-yl)ethenyl]-1-(tetrahydro-2H-pyran-2-yl)-1H-indazole
(E)-3-[2-(Pyridin-2-yl)ethenyl]-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-6-amine
1-METHYL-1H-INDAZOL-6-YLAMINE
1of3
Global( 315)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Zison Pharmaceutical (Shandong) Co., Ltd. | +86-0086-531-88259693 +86-18660188356 | maguanglei@zisonpharm.com | China | 53 | 58 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21695 | 55 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
Anqing Chico Pharmaceutical Co., Ltd. | 15380796838 | chloewu@chicopharm.cn | CHINA | 341 | 58 |
career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
Anhui Dexinjia Biopharm Co., Ltd | +86-531-82375818 +86-15064153060 | alice@jndxj.com | China | 309 | 58 |
Jinan Shengqi pharmaceutical Co,Ltd | 86+18663751872 | christine@shengqipharm.com | CHINA | 491 | 58 |
Accela ChemBio Inc. | (+1)-858-699-3322 | info@accelachem.com | United States | 19965 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
View Lastest Price from 6-Nitroindazole manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2025-04-19 | 6-Nitroindazole
7597-18-4
|
US $100.00-2000.00 / kg | 0.10000000149011612kg | 98% | 2MT per month | Anhui Dexinjia Biopharm Co., Ltd | ||
2024-12-27 | 6-Nitroindazole
7597-18-4
|
US $0.00-0.00 / kg | 1kg | 98% | 1 ton | Nanjing Fred Technology Co., Ltd | ||
2024-12-01 | 6-Nitro-1H-indazole
7597-18-4
|
US $0.00-0.00 / kg | 1kg | ≥98% by HPLC | 100kg/month | Zison Pharmaceutical (Shandong) Co., Ltd. |
- 6-Nitroindazole
7597-18-4
- US $100.00-2000.00 / kg
- 98%
- Anhui Dexinjia Biopharm Co., Ltd
- 6-Nitroindazole
7597-18-4
- US $0.00-0.00 / kg
- 98%
- Nanjing Fred Technology Co., Ltd
- 6-Nitro-1H-indazole
7597-18-4
- US $0.00-0.00 / kg
- ≥98% by HPLC
- Zison Pharmaceutical (Shandong) Co., Ltd.
7597-18-4(6-Nitroindazole)Related Search:
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1H-Indazole, 6-nitro-
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6-Nitroindazole ,97%
6-Nitroindazole,98%
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6-Nitroindazole 97%
6-Nitroindazole>
6-Nitrobrazol
Pazopanib Impurity 59
6-NITRO-1H-INDAZOLE
7597-18-4
9597-18-4
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