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ChemicalBook >> CAS DataBase List >>1-Hydroxybenzotriazole hydrate

1-Hydroxybenzotriazole hydrate

CAS No.
123333-53-9
Chemical Name:
1-Hydroxybenzotriazole hydrate
Synonyms
1-HYDROXYBENZOTRIAZOLE MONOHYDRATE;HOBT H2O;HOBT HYDRATE;HOBT.H20;1H-benzo[d][1,2,3]triazol-1-ol hydrate;N-HYDROXYBENZOTRIAZOLE HYDRATE;HOBTM;e hydrate;HOBT MONOHYDRATE;TIMTEC-BB SBB000114
CBNumber:
CB8775919
Molecular Formula:
C6H7N3O2
Molecular Weight:
153.14
MDL Number:
MFCD00065690
MOL File:
123333-53-9.mol
MSDS File:
SDS
Last updated:2024-12-22 17:53:22

1-Hydroxybenzotriazole hydrate Properties

Melting point 155-158 °C(lit.)
Boiling point 248.8°C (rough estimate)
Density 1.065 g/cm
refractive index 1.6910 (estimate)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility DMF: 100 mg/mL, clear
form Solid
color White to Off-White
Water Solubility slightly soluble
BRN 4515
Stability Hygroscopic
CAS DataBase Reference 123333-53-9(CAS DataBase Reference)
FDA UNII

SAFETY

Risk and Safety Statements

Symbol(GHS)  sòng bạc tiền thậtLiên kết đăng nhậpsòng bạc tiền thậtLiên kết đăng nhập
GHS02,GHS07
Signal word  Danger
Hazard statements  H207-H319-H412
Precautionary statements  P210-P212-P230-P233-P280-P370+P380+P375-P501
Hazard Codes  F
Risk Statements  5-11-R5-R11-44-1
Safety Statements  15-16-35-7/9-33-S7/9-S33-S16-60-37-26
RIDADR  UN 3380 4.1/PG 1
WGK Germany  -
4.10-8
Hazard Note  Highly Flammable
HS Code  29339980

1-Hydroxybenzotriazole hydrate price More Price(21)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 157260 1-Hydroxybenzotriazole hydrate wetted with not less than 14 wt. % water, 97% 123333-53-9 25g $81.1 2025-03-01 Buy
Sigma-Aldrich 157260 1-Hydroxybenzotriazole hydrate wetted with not less than 14 wt. % water, 97% 123333-53-9 100g $191 2025-03-01 Buy
Sigma-Aldrich 711489 1-Hydroxybenzotriazole hydrate wetted with not less than 20 wt. % water, 97% 123333-53-9 50g $133 2025-03-01 Buy
Sigma-Aldrich 711489 1-Hydroxybenzotriazole hydrate wetted with not less than 20 wt. % water, 97% 123333-53-9 250g $450 2025-03-01 Buy
Sigma-Aldrich 711489 1-Hydroxybenzotriazole hydrate wetted with not less than 20 wt. % water, 97% 123333-53-9 1kg $1400 2025-03-01 Buy
Product number Packaging Price Buy
157260 25g $81.1 Buy
157260 100g $191 Buy
711489 50g $133 Buy
711489 250g $450 Buy
711489 1kg $1400 Buy

1-Hydroxybenzotriazole hydrate Chemical Properties,Uses,Production

Chemical Properties

White to off-white powder

Uses

1-Hydroxybenzotriazole hydrate can be used as a condensation reagent to prepare:

  • Poly-γ-glutamic acid methyl ester from a dimer of γ-glutamic acid.
  • Oxadiazoles via cyclo condensation of amidoximes with trifluoroacetic anhydride or benzoic acid derivatives.

Uses

A common additive for peptide coupling.

Uses

additive for oligonucleotide couplings and in racemization-free peptide couplings

General Description

1-Hydroxybenzotriazole is a coupling reagent used to synthesize amides by the condensation reaction between the activated ester/acid and the amino group of protected amino acids. It is also used as a racemization suppressor during peptide synthesis.

1-Hydroxybenzotriazole hydrate Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 432)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Mojin Biotechnology Co., Ltd
+8613288715578 sales@hbmojin.com China 12452 58
Hebei Yanxi Chemical Co., Ltd.
+8617531190177 peter@yan-xi.com China 5993 58
Hebei Guanlang Biotechnology Co,.LTD
+8619930503252 daisy@crovellbio.com China 5964 58
Capot Chemical Co.,Ltd.
571-85586718 +8613336195806 sales@capotchem.com China 29797 60
Shanghai Daken Advanced Materials Co.,Ltd
+86-371-66670886 info@dakenam.com China 15371 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21695 55
Zjartschem
+86-571-8723 8903 jocelynpan@zjarts.com jocelynpan@zjarts.com CHINA 993 58
Shanxi Naipu Import and Export Co.,Ltd
+86-13734021967 +8613734021967 kaia@neputrading.com China 1011 58
Shanghai Zheyan Biotech Co., Ltd.
18017610038 zheyansh@163.com CHINA 3620 58
career henan chemical co
+86-0371-86658258 sales@coreychem.com China 29914 58

View Lastest Price from 1-Hydroxybenzotriazole hydrate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
sòng bạc tiền thậtLiên kết đăng nhập 2024-11-22 1-Hydroxybenzotriazole hydrate
123333-53-9
US $30.00-10.00 / kg 1kg 0.99 10 tons Hebei Yanxi Chemical Co., Ltd.
sòng bạc tiền thậtLiên kết đăng nhập 2024-09-26 1-Hydroxybenzotriazole hydrate
123333-53-9
US $0.00 / KG 1KG 99% 50000KG/month Hebei Mojin Biotechnology Co., Ltd
sòng bạc tiền thậtLiên kết đăng nhập 2024-09-18 1-Hydroxybenzotriazole hydrate
123333-53-9
US $100.00-50.00 / KG 1KG 99% 10000kg Hebei Guanlang Biotechnology Co,.LTD
HOBTM 1H-1,2,3-benzotriazol-1-ol hydrate solution 1-HYDROXYBENZOTRIAZOLE 15 WT. % SOLUTI& 1H-Benzo[d][1,2,3]triazol-1-ol xhydrate HOBT.H2O1-Hydroxybenzotriazole hydrate 1-Hydroxybenzotriazole hydrate wetted with not less than 20 wt. % water, 97% 1-Hydroxybenzotriazole hydrate HOBT hydrate 1-Hydroxybenzotriazole hydrate >=97.0% (T) HOBT monohydrate (1-hydroxybenzotriazole.H2O) 1-Hydroxybenzotriazole hydrate(< 5 ppm hydrazine)wetted with not less than 20 wt. % water≥ 99% (HPLC) HOBt hydrate (<5 ppm hydrazine) N-HYDROXYBENZOTRIAZOL MONOHYDRATE N-HYDROXYBENZOTRIAZOLE MONOHYDRATE N-HYDROXYBENZOTRIAZOLE H2O TIMTEC-BB SBB000114 1-Hydroxybenzotriazole99%Puriss 1-Hydroxybenzotriazole hydrate, ca. 6% water, 98% Hydroxy-1,2,3-Benzotriazole 2592-95-2 1-HYDROXY BENZOTRIAZOLE MONOHYDATE HOBt(hydrate) N-Hydroxybenzotnazole Hydrate 1-HYDROXYBENZOTRIAZOLE HYDRATE (WATER CONTENT BETWEEN 10-13%) 1-Hydroxybenzotriazole Monohydrous 1-Hydroxybenzotriazole Hyrate 1-Hydroxybenzotriazole hydrate, contains 11-16% water, 98% 1-Hydroxybenzotriazole (HOBt) hydrate 1-Hydroxybenzotriazole hydrate (HOBt) N-Hydroxybenzotriazole monohydrate (HOBt) 1-Hydroxy-1H-benzotriazole Hydrate 1-Oxy-benztriazol Hydrate Benzotriazol-1-ol Hydrate 1-Hydroxybenzotriazole hydrate, 98% (dry wt), water >20% 1-Hydroxybenzotriazole hydrate ,99% 1-HYDROXYBENZOTRIAZOLE HYDRATE, 98%, CONTAINS 11-16% WATER 1-Hydroxybenzotriazole hydrate ,98% N-Hydroxybenzotrizole Monohydrate 1H-1,2,3-benzotriazole-1,4-diol 1H-1,2,3-BENZOTRIAZOL-1-OL HYDRATE 1H-BENZOTRIAZOLE, 1-HYDROXY-, HYDRATE 1-HYDROXYBENZOTRIAZOL MONOHYDRATE 1-HYDROXYBENZOTRIAZOLE N-HYDRATE 1-HYDROXYBENZOTRIAZOLE HYDRATE HOBT MONOHYDRATE HOBT hydrate [1-Hydroxybenzotriazole hydrate] 1-Hydroxybenzotriazole Hydrat HOBT.H20 1-Hydroxybenzotriazole hydrate 1,2,3-BENZOTRIAZOL-1-OL MONOHYDRATE e hydrate HOBT.H20 1-Hydroxybenzotriazole hydrate,≥97.0% 1-Hydroxybenzotriazole hydrate USP/EP/BP HoBt.H2O [ 123333-53-9 HOBT,1-Hydroxybenzotriazole hydrate HOBT Monohydrate pure, 99% HOBT HYDRATE HOBT H2O 1H-benzo[d][1,2,3]triazol-1-ol hydrate HOBT.H20 1-HYDROXYBENZOTRIAZOLE MONOHYDRATE N-HYDROXYBENZOTRIAZOLE HYDRATE
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