ChemicalBook >> CAS DataBase List >>Ethyl cyanoformate
Ethyl cyanoformate
- CAS No.
- 623-49-4
- Chemical Name:
- Ethyl cyanoformate
- Synonyms
- NSC 65347;C2H5OC(O)CN;cyanoformate;ETHYL CYANOFORMATE;Ethylcyanoformate,99%;ethyl carbonocyanidate;Ethyl cyanoformate 99%;Ethoxycarbonyl Cyanide;Ethyl cyanocarboxylate;Ethyl Cyanoformate >
- CBNumber:
- CB8854001
- Molecular Formula:
- C4H5NO2
- Molecular Weight:
- 99.09
- MDL Number:
- MFCD00001836
- MOL File:
- 623-49-4.mol
- MSDS File:
- SDS
Last updated:2024-04-23 13:52:06
Boiling point | 115-116 °C (lit.) |
---|---|
Density | 1.003 g/mL at 25 °C (lit.) |
refractive index |
n |
Flash point | 76 °F |
storage temp. | Inert atmosphere,2-8°C |
solubility | Miscible with chloroform and methanol. |
form | Liquid |
Specific Gravity | 1.01 |
color | Clear colorless |
Sensitive | Moisture Sensitive |
BRN | 635955 |
Exposure limits | NIOSH: IDLH 25 mg/m3 |
CAS DataBase Reference | 623-49-4(CAS DataBase Reference) |
FDA UNII | |
NIST Chemistry Reference | |
EPA Substance Registry System |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS02,GHS05 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Signal word | Danger | |||||||||
Hazard statements | H226-H314 | |||||||||
Precautionary statements | P210-P280-P303+P361+P353-P305+P351+P338+P310 | |||||||||
Hazard Codes | T,F | |||||||||
Risk Statements | 10-23/24/25-34-36/37/38 | |||||||||
Safety Statements | 26-36/37/39-45-24/25-16-7/9 | |||||||||
RIDADR | UN 3275 6.1/PG 2 | |||||||||
WGK Germany | 3 | |||||||||
F | 10-19-21 | |||||||||
TSCA | Yes | |||||||||
HazardClass | 6.1 | |||||||||
PackingGroup | II | |||||||||
HS Code | 29269090 | |||||||||
NFPA 704 |
|
Ethyl cyanoformate price More Price(24)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | E18859 | Ethyl cyanoformate 99% | 623-49-4 | 10g | $86.5 | 2025-03-01 | Buy |
Sigma-Aldrich | E18859 | Ethyl cyanoformate 99% | 623-49-4 | 50g | $114 | 2025-03-01 | Buy |
TCI Chemical | C1266 | Ethyl Cyanoformate >98.0%(GC) | 623-49-4 | 5g | $35 | 2025-03-01 | Buy |
TCI Chemical | C1266 | Ethyl Cyanoformate >98.0%(GC) | 623-49-4 | 25g | $98 | 2025-03-01 | Buy |
Alfa Aesar | L15777 | Ethyl cyanoformate, 99% | 623-49-4 | 5g | $39.1 | 2025-03-01 | Buy |
Ethyl cyanoformate Chemical Properties,Uses,Production
Chemical Properties
Clear Colourless LiquidUses
Ethyl cyanoformate can be used as a cyanide source for the cyanation of:
- Activated olefins in the presence of a titanium catalyst.
- Carbonyl compounds catalyzed by 4-dimethylaminopyridine (DMAP) to yield corresponding cyanohydrin carbonates under metal-free and solvent-free conditions.
- Aldehydes and 2,2,2-trifluoroacetophenone catalyzed by N-heterocyclic carbene (NHC) to yield corresponding cyanohydrins ethyl carbonates.
Uses
Ethyl Cyanoformate (cas# 623-49-4) is a compound useful in organic synthesis.Uses
Ethyl cyanoformate is used as reagent in the preparation of N-substituted amindinoformic acid and ethyl-4-quinazoline -2-carboxylate.Application
Ethyl cyanoformate can be used as a cyanide source for the cyanation of:
Activated olefins in the presence of a titanium catalyst.
Carbonyl compounds catalyzed by 4-dimethylaminopyridine (DMAP) to yield corresponding cyanohydrin carbonates under metal-free and solvent-free conditions.
Aldehydes and 2,2,2-trifluoroacetophenone catalyzed by N-heterocyclic carbene (NHC) to yield corresponding cyanohydrins ethyl carbonates.
Ethyl cyanoformate is a general cyanating agent. It can be used in the nucleophilic addition of cyanide to carbonyl compounds, oxidative cyanation of tertiary amines and in the synthesis of β-cyano-substituted acrylates from alkynes.
Purification Methods
Dissolve the cyanoformate in Et2O, dry it over Na2SO4, filter, evaporate and distil it [Malachowsky et al. Chem Ber 70 1016 1937, Adickes et al. J Prakt Chem [2] 133 313 1932, Grundmann et al. Justus Liebigs Ann Chem 577 77 1952]. [Beilstein 2 IV 1862.]Precautions
Moisture sensitive. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with strong acids, strong bases, strong oxidizing agents and strong reducing agents.Ethyl cyanoformate Preparation Products And Raw materials
Raw materials
Preparation Products
ETHANOL-1,1,2,2-D4-AMINE
Ethyl 2-cyclohexyl-2-oxoacetate
ETHYL 4-BROMOTHIAZOLE-2-CARBOXYLATE
ETHYL 5-PYRIMIDINECARBOXYLATE 98
ETHYL 2-(2-CHLOROPHENYL)ACETATE
1of3
Global( 260)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21689 | 55 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32686 | 60 |
career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
Biochempartner | 0086-13720134139 | candy@biochempartner.com | CHINA | 967 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49391 | 58 |
Antai Fine Chemical Technology Co.,Limited | 18503026267 | info@antaichem.com | CHINA | 9641 | 58 |
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21149 | 58 |
Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 | sales@tnjchem.com | China | 34572 | 58 |
View Lastest Price from Ethyl cyanoformate manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-06-15 | Ethyl cyanoformate
623-49-4
|
US $157.00 / ASSAYS | 1KG | 99% | 10 tons | Baoji Guokang Bio-Technology Co., Ltd. | ||
2023-01-15 | EthylCarbonocyanidate
623-49-4
|
US $0.00 / KG | 1KG | 97.6% | 100 tons | Honest Joy Holdings Limited
|
||
2022-07-13 | Ethyl cyanoformate
623-49-4
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd |
- Ethyl cyanoformate
623-49-4
- US $157.00 / ASSAYS
- 99%
- Baoji Guokang Bio-Technology Co., Ltd.
- EthylCarbonocyanidate
623-49-4
- US $0.00 / KG
- 97.6%
- Honest Joy Holdings Limited
- Ethyl cyanoformate
623-49-4
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
623-49-4(Ethyl cyanoformate)Related Search:
1of4
Ethyl carbonocyanidoate
Ethyl cyanoforMate, 99% 10GR
Ethyl cyanoforMate, 99% 50GR
ethyl carbonocyanidate
Ethyl cyanoforMate, 98%+
Ethyl cyanoformate 99%
CYANOFORMIC ACID ETHYL ESTER
ETHYL CYANOFORMATE
2-ethoxy-2-oxoacetonitrile
[(Cyanocarbonyl)oxy]ethane
C2H5OC(O)CN
carbocyanidicacidethylester
Carbonocyanidic acid, ethyl ester
carbonocyanidicacid,ethylester
Formic acid, cyano-, ethyl ester
Nitriloaceticacidethylester
Ethoxycarbonyl Cyanide
NSC 65347
Ethylcyanoformate,99%
cyanoformate
Ethyl cyanocarboxylate
Ethyl Cyanoformate >
Formicacid, cyano-, ethyl este
623-49-4
NCCOOC2H5
C4H5NO2
NCCO2C2H5
NCCO2CH2CH3
Esters
Organic Building Blocks
Building Blocks
C2 to C5
Carbonyl Compounds
C2 to C5
Carbonyl Compounds
Chemical Synthesis
Organic Building Blocks
Aliphatics
Esters
C2 to C5
Carbonyl Compounds
Building Blocks
john's