4-メトキシフェノール 化学特征,用处語,生産方式
外観
红色～わずかにうすい黄色, 結晶～結晶性粉末
定義
本品は、フェノール(*)の誘導体であり、次の化学式で表される。
参照表现称号：フェノール
消融性
水に微溶 (4g/100ml 25℃).エタノール, エーテルに易溶。エタノール及びアセトンに溶けやすく、水に溶けにくい。
用处
有機分解质料、安靖剤(重合制止剤)。1. アクリル酸エステル、アクリルニトリルモノマーの重合避免剤 增加量は10～500ppm。2. 油脂、脂肪酸、石けん等の酸化避免剤。3. エチルセルロースへの0.5～3%增加により粘度、柔軟性等の坚持に効果。
用处
重合避免剤、香料、プラスチック增加剤
化粧品の成份用处
還元剤、酸化避免剤、香料
効能
色素沈着改良薬
化学的特征
4-Methoxyphenol is a colorless to white, waxy solid with an odor of caramel and phenol. It is a combustible solid. It is used as an inhibitor for acrylic monomers and as a stabilizer for chlorinated hydrocarbons, ethyl cellulose, and UV inhibitors.
適応症
Mequinol (4-hydroxyanisole) is a substrate of the enzyme tyrosinase and acts
as a competitive inhibitor of melanogenesis.
分解
4-Methoxyphenol was synthesised according to Oxidation with H2O2 and a Diselenide catalyst.
p-Anisaldehyde (50 mmol) is dissolved in CH2Cl2 (100mL) and (o-NO2PhSe)2 (2 mmol) and 30% H2O2 (13mL, 128 mmol) are added. The mixture is stirred magnetically at room temperature (water bath) for 30 minutes. Insoluble catalyst is removed by filtration and washed with CH2Cl2 (20mL) and water (20mL). It can be reused after drying. To the filtrate and washings, water (100mL) is added, and the layers are separated after shaking. The organic layer is washed subsequently with 10% NaHSO3 (100mL), 10% Na2CO3 (100mL), water (100mL) and dried over Na2SO4. 4-methoxyphenol is obtained by alkaline hydrolysis of the residue. Yield: 93%.
反応性
4-methoxyphenol(4-MP) may be used in the synthesis of butylated hydroxy anisoles via alkylation with methyl tert-butyl ether over a non-zeolitic solid acidic catalyst. This process is eco-friendly when compared to the Friedel-Crafts alkylation reaction. 4-MP may also react with aqueous nitrous acid to form 2-nitro-4-methoxyphenol and benzoquinone in varying ratios depending on the reaction conditions. 4-MP can be used as a building block in designing β-cyclodextrin 4-methoxyphenol conjugates that can be potential ligands for drug complexation.
普通的な説明
Pink crystals or white waxy solid.
空気と水の反応
Sensitive to moisture. Water soluble.
反応プロフィール
4-Methoxyphenol can react with oxidizing materials.
危険性
Eye irritant and skin damage.
安康ハザード
4-Methoxyphenol is expected to
cause liver and renal toxicity with narcosis, but
only at high levels of exposure.
火災危険
Combustible
宁静性プロファイル
Poison by
intraperitoneal route. A skin irritant. When
heated to decomposition it emits acrid
smoke and fumes. See also ETHERS.
輸送方式
UN3335 Aviation regulated solid, n.o.s., Hazard
class: 9; Labels: 9-Miscellaneous hazardous material,
Technical Name Required.
純化方式
Crystallise 4-methoxyphenol from *benzene, pet ether or H2O, and dry it under vacuum over P2O5 at room temperature. Sublime it in vacuo. [Wolfenden et al. J Am Chem Soc 109 463 1987, Beilstein 6 IV 5717.]
4-メトキシフェノール 下贱と下贱の製品情報
原资料
準備製品