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ChemicalBook >> CAS DataBase List >>7-Nitroindazole

7-Nitroindazole

CAS No.
2942-42-9
Chemical Name:
7-Nitroindazole
Synonyms
7-NITRO-1H-INDAZOLE;7-NI;NITROINDAZOLE;7-NITROINDAZOLE;INDAZOLE, 7-NITRO-;7-nitro-1h-indazol;7-Nitroindazole>7-NITROINDAZOLE 97+%;1H-Indazole, 7-nitro-;7-Nitro-1H-indazole,98%
CBNumber:
CB6306238
Molecular Formula:
C7H5N3O2
Molecular Weight:
163.13
MDL Number:
MFCD00022789
MOL File:
2942-42-9.mol
MSDS File:
SDS
Last updated:2024-12-15 15:12:15

7-Nitroindazole Properties

Melting point 185-186°C
Boiling point 290.19°C (rough estimate)
Density 1.4141 (rough estimate)
refractive index 1.5500 (estimate)
storage temp. -20°C
solubility Soluble to 100 mM in DMSO and to 20 mM in ethanol
pka 10.03±0.40(Predicted)
form powder to crystal
color Light yellow to Brown
Water Solubility slightly soluble
BRN 6809
InChI InChI=1S/C7H5N3O2/c11-10(12)6-3-1-2-5-4-8-9-7(5)6/h1-4H,(H,8,9)
InChIKey PQCAUHUKTBHUSA-UHFFFAOYSA-N
SMILES N1C2=C(C=CC=C2[N+]([O-])=O)C=N1
CAS DataBase Reference 2942-42-9(CAS DataBase Reference)
EWG's Food Scores
FDA UNII
NIST Chemistry Reference

SAFETY

Risk and Safety Statements

Symbol(GHS)  sòng bạc tiền thậtLiên kết đăng nhậpsòng bạc tiền thậtLiên kết đăng nhập
GHS06,GHS08
Signal word  Danger
Hazard statements  H301-H319-H351-H360
Precautionary statements  P201-P301+P310+P330-P305+P351+P338
Hazard Codes  T
Risk Statements  60-40
Safety Statements  53-22-36/37/39-45
RIDADR  UN 2811 6.1/PG 3
WGK Germany  3
RTECS  NK7962200
HazardClass  IRRITANT
PackingGroup 
HS Code  29339900
NFPA 704
1
2 0

7-Nitroindazole price More Price(53)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich N7778 7-Nitroindazole ≥98% 2942-42-9 1g $324 2025-03-01 Buy
Sigma-Aldrich N7778 7-Nitroindazole ≥98% 2942-42-9 5g $1050 2025-03-01 Buy
TCI Chemical N0827 7-Nitroindazole >97.0%(GC) 2942-42-9 1g $61 2025-03-01 Buy
TCI Chemical N0827 7-Nitroindazole >97.0%(GC) 2942-42-9 5g $252 2025-03-01 Buy
Alfa Aesar L07970 7-Nitro-1H-indazole, 98% 2942-42-9 1g $77.3 2024-06-20 Buy
Product number Packaging Price Buy
N7778 1g $324 Buy
N7778 5g $1050 Buy
N0827 1g $61 Buy
N0827 5g $252 Buy
L07970 1g $77.3 Buy

7-Nitroindazole Chemical Properties,Uses,Production

Description

7-Nitroindazole is a non-selective inhibitor of NOS isoforms in vitro. However, it shows good anti-nociceptive effects in vivo without affecting blood pressure via inhibition of eNOS. The IC50 values for inhibition of rat nNOS, bovine eNOS, and rat iNOS are 0.71, 0.78, and 5.8 μM, respectively.

Chemical Properties

yellow powder or Yellow orange solid soluble in DMSO.

Uses

7-nitroindazole is a specific inhibitor of neural nitric oxide synthase (nNOS), an enzyme that converts arginine to citrulline and nitric oxide (NO) in neuronal tissue. NO is a key player in the hippocampal long-term potentiation (LTP) and in general cell signaling.

Definition

7-Nitroindazole is a heterocyclic small molecule containing an indazole ring that has been nitrated at the 7 position. It is a potent, selective brain inhibitor of mouse cerebellar Nitric Oxide Synthase, a hemoprotein enzyme that, in neuronal tissue, converts arginine to citrulline and nitric oxide (NO).

Biological Activity

Sodium salt of the non-selective NOS inhibitor 7-nitroindazole (7-Nitroindazole).
570-24-1
2942-42-9
Synthesis of 7-Nitroindazole from 2-Methyl-6-nitroaniline

7-Nitroindazole Preparation Products And Raw materials

Global( 252)Suppliers
Supplier Tel Email Country ProdList Advantage
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd
+8613580539051 joe@yuhengpharm.com CHINA 21149 58
Capot Chemical Co.,Ltd.
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Hangzhou FandaChem Co.,Ltd.
008657128800458; +8615858145714 fandachem@gmail.com China 9352 55
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32480 60
Accela ChemBio Inc.
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Chongqing Chemdad Co., Ltd
+86-023-61398051 +8613650506873 sales@chemdad.com China 39916 58
Alchem Pharmtech,Inc.
8485655694 sales@alchempharmtech.com United States 63711 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 47465 58
career henan chemical co
+86-0371-86658258 15093356674; factory@coreychem.com China 29826 58
SIMAGCHEM CORP
+86-13806087780 sale@simagchem.com China 17367 58

View Lastest Price from 7-Nitroindazole manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
sòng bạc tiền thậtLiên kết đăng nhập 2022-07-02 7-Nitroindazole
2942-42-9
US $15.00-10.00 / KG 1KG 99%+ HPLC Monthly supply of 1 ton Zhuozhou Wenxi import and Export Co., Ltd
sòng bạc tiền thậtLiên kết đăng nhập 2021-01-10 7-Nitroindazole
2942-42-9
US $6.68 / KG 1KG 97%-99% 1kg-1000kg Career Henan Chemical Co
  • sòng bạc tiền thậtLiên kết đăng nhập
  • 7-Nitroindazole
    2942-42-9
  • US $15.00-10.00 / KG
  • 99%+ HPLC
  • Zhuozhou Wenxi import and Export Co., Ltd
7-Nitroindazole, 97% 25MG 7-Nitro-1H-indazole,98% 1H-Indazole, 7-nitro- 7-nitro-1h-indazol INDAZOLE, 7-NITRO- 7-NITROINDAZOLE 7-NI 7-NITROINDAZOLE INDAZOLE, 7-NITRO-INHIBI TOR OF BRAIN NI NITROINDAZOLE 7-NITROINDAZOLE 97+% 7-Nitro-1H-indazole, 97 % 7-Nitroindazole, 97%, Selective inhibitor of nitric oxide Nitroindazole Nitroindazole 7-Nitroindazole> 7-NITRO-1H-INDAZOLE 7-Nitroindazole, 96% (Custom work) 2942-42-9 C7H4N3O2Na Selective inhibitor of nitric oxide synthase from mouse brain. Enzyme Inhibitors Enzyme Inhibitors by Enzyme Enzymes, Inhibitors, and Substrates L to O Nitric Oxide Synthase Biochemicals and Reagents BioChemical Inhibitors Nitric Oxide Reagents Nitric Oxide All Inhibitors Indazoles Heterocyclic Compounds Signalling Indoles and derivatives
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